STRASBOURG/PARIS, Dec 13 (Reuters) – The suspected gunman, who killed three people at a Christmas market in Strasbourg, has been killed, two police sources said on Thursday, ending his 48-hours on the run.

Cherif Chekatt was killed in the Neudorf/Meinau area of the city after a police operation was launched around 2100 hrs (2000 GMT) on Thursday about 2 kilometers from where he launched his attack on Tuesday.

Chekatt was killed after firing on police officers, who returned fire, one of the sources said.

Reuters reporters near the scene heard three to four gunshots after a huge police operation with armed forces from the BRI and RAID units. A police helicopter had been circling overhead.

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Deadly shooting at French Christmas market

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In this image made from video, emergency services arrive on the scene of a Christmas market in Strasbourg, France, Tuesday, Dec. 11, 2018. A French regional official says that a shooting in Strasbourg has left at least one dead and several wounded in the city center near a world-famous Christmas market. The prefect of France’s Bas-Rhin region says the gunman, who is still at large, has been identified. Authorities haven’t given a motive for the shooting. (AP Photo)

Tis picture taken with a mobile phone shows rescuers treating an injured person in the streets of Strasbourg, eastern France, after a shooting breakout, on December 11, 2018. – Two persons has been killed and 11 people injured in a shooting today near a Christmas market in the eastern French city of Strasbourg, police said, adding that the suspected gunman was on the run. (Photo by François D’ASTIER / AFP) (Photo credit should read FRANCOIS D’ASTIER/AFP/Getty Images)

Police, firefighters and emergency services intervene on Place Gutenberg after a shooting on December 11, 2018 in Strasbourg, eastern France. – At least two people have been killed and 11 critically wounded in a shooting in the French city of Strasbourg, police said, updating the number of victims. (Photo by Patrick HERTZOG / AFP) (Photo credit should read PATRICK HERTZOG/AFP/Getty Images)

In this image made from video provided by CMM, people lay on the ground after a shooting at a Christmas market in Strasbourg, France, Tuesday, Dec. 11, 2018. A French regional official says that a shooting in Strasbourg has left at least one dead and several wounded in the city center near a world-famous Christmas market. The prefect of France’s Bas-Rhin region says the gunman, who is still at large, has been identified. Authorities haven’t given a motive for the shooting. (CMM via AP)

Police secure a street and the surrounding area after a shooting in Strasbourg, France, December 11, 2018. REUTERS/Vincent Kessler

Ambulance is seen at the scene of shooting in Strasbourg, France, December 11, 2018. REUTERS/Vincent Kessler

Police officer secures a street and the surrounding area after a shooting in Strasbourg, France, December 11, 2018. REUTERS/Vincent Kessler

Police secure a street and the surrounding area after a shooting in Strasbourg, France, December 11, 2018. REUTERS/Vincent Kessler

Police secure a street and the surrounding area after a shooting in Strasbourg, France, December 11, 2018. REUTERS/Vincent Kessler

Police officers secure a street and the surrounding area after a shooting in Strasbourg, France, December 11, 2018. REUTERS/Vincent Kessler

Police secure a street and the surrounding area after a shooting in Strasbourg, France, December 11, 2018. REUTERS/Vincent Kessler

Soldiers secure area where a suspect is sought after a shooting in Strasbourg, France, December 11, 2018. REUTERS/Vincent Kessler

Police officer secures a street and the surrounding area after a shooting in Strasbourg, France, December 11, 2018. REUTERS/Vincent Kessler

Police officer secures a street and the surrounding area after a shooting in Strasbourg, France, December 11, 2018. REUTERS/Vincent Kessler

Police secure a street and the surrounding area after a shooting in Strasbourg, France, December 11, 2018. REUTERS/Vincent Kessler

Rescue teams work at the scene of shooting in Strasbourg, France, December 11, 2018. REUTERS/Vincent Kessler

Police, firefighters and emergency services intervene on Place Gutenberg, near the Strasbourg Cathedral (in the background) after a shooting on December 11, 2018 in Strasbourg, eastern France. – At least two people have been killed and 11 critically wounded in a shooting in the French city of Strasbourg, police said, updating the number of victims. (Photo by Patrick HERTZOG / AFP) (Photo credit should read PATRICK HERTZOG/AFP/Getty Images)

A military stands in the streets of Strasbourg, eastern France, after a shooting breakout, on December 11, 2018. – Two persons has been killed and 11 people injured in a shooting today near a Christmas market in the eastern French city of Strasbourg, police said, adding that the suspected gunman was on the run. (Photo by Frederick FLORIN / AFP) (Photo credit should read FREDERICK FLORIN/AFP/Getty Images)

Policemen walk in the streets of Strasbourg, eastern France, after a shooting breakout, on December 11, 2018. – At least two people have been killed and 11 critically wounded in a shooting in the French city of Strasbourg, police said, updating the number of victims. (Photo by Frederick FLORIN / AFP) (Photo credit should read FREDERICK FLORIN/AFP/Getty Images)

Policemen speak with a military in the streets of Strasbourg, eastern France, after a shooting breakout, on December 11, 2018. – At least two people have been killed and 11 critically wounded in a shooting in the French city of Strasbourg, police said, updating the number of victims. (Photo by Frederick FLORIN / AFP) (Photo credit should read FREDERICK FLORIN/AFP/Getty Images)

Police, firefighters and emergency services intervene on Place Gutenberg after a shooting on December 11, 2018 in Strasbourg, eastern France. – At least two people have been killed and 11 critically wounded in a shooting in the French city of Strasbourg, police said, updating the number of victims. (Photo by Patrick HERTZOG / AFP) (Photo credit should read PATRICK HERTZOG/AFP/Getty Images)

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The death toll from Tuesday’s attack rose to three as police on Thursday combed the city in the east of France for a second day and manned checkpoints on the German border.

Police issued a wanted poster in multiple languages for Chekatt, who was the main suspect in the attack and who had been on a watchlist as a potential security threat.

Authorities say the 29-year-old was known to have developed radical religious views while in jail.

Earlier in the day armed and masked police swooped on Strasbourg neighborhoods with elite RAID officers fanning out across three locations in late afternoon, including the area where Chekatt was last seen.

The Paris prosecutor’s office said Chekatt’s parents and two brothers were being held in custody.

Two of his sisters in Paris were also questioned on Thursday and one of their homes was searched, a judicial source said.

(Additional reporting by Gilbert Reilhac in Strasbourg, Antony Paone, Richard Lough, Emmanuel Jarry in Paris and Michelle Martin and Paul Carrel in Berlin; Writing by John Irish Editing by Richard Balmforth)

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